S S A R

22nd ANNUAL SCANDINAVIAN ATHEROSCLEROSIS CONFERENCE

Programme for the 2016 meeting

 

Revised Abstract Book

Wednesday, April 13, 2016

16.00 – 18.00

Arrival, registration and coffee (dining room until 17.45)

 

18.00 – 19.30

 

Dinner

 

19.30 – 19.35

 

Christina Christoffersen (Denmark)
Welcome

 

 

THE 2016 NIKKILÄ MEMORIAL LECTURE

 

19.35 – 19.40

Introduction of the 2016 Nikkilä Lecturer
Alexandra Krettek (Sweden)

 

19.40 – 20.25

2016 Nikkilä Lecture
Brown adipose tissue: A novel target to comBAT cardiometabolic disease
Professor Patrick Rensen (The Netherlands)

Patrick Rensen

 

20.25 – 20.45

Discussion

 

20.45 –

Pub will be open

 

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Thursday, April 14, 2016

08.00 – 09.00

Breakfast

 

Session I. CARDIOVASCULAR DISEASE
Organized and chaired by Kirsten Holven (Norway) and Emil D. Bartels (Denmark)

09.00 – 09.25

Cardiovascular disease and dementia – an important relationship in the aging population
Ruth Frikke-Schmidt
(Denmark)

09.25 – 09.30

Discussion

09.30 – 09.45

Loss – of – function mutations in APOC3, remnant cholesterol, LDL cholesterol, and risk of ischemic vascular disease
Anders Berg Wulff (Denmark)

09.45 – 10.00

ACC/AHA guidelines superior to ESC/EAS guidelines for primary prevention with statins: The Copenhagen General Population Study
Martin Bødtker Mortensen (Denmark)

10.00 – 10.15

Maternal metabolic outcomes six years after pregnancy in women with a history of hypertensive pregnancy disorders
Jeanine Roeters van Lennep (The Netherlands)

10.15 – 10.30

A novel long residence time CCR2 antagonist inhibits atherogenesis in apoE deficient mice
Ilse Bot (The Netherlands)

10.30 – 11.15

Coffee, posters and exhibitions

 

11.15 – 11.40

Effect of maternal cardiovascular conditions and risk factors on offspring cardiovascular disease
Wulf Palinski (USA)

11.40 – 11.45

Discussion

11.45 – 12.00

The water channel AQP1 is associated with human atherosclerotic vascular lesions and attenuates progression of atherosclerosis in males independent of blood pressure
Jane Stubbe (Denmark)

12.00 – 12.15

HDL Cholesterol Efflux Does Not Predict Cardiovascular Risk in Hemodialysis Patients
Sanam Ebtehaj (The Netherlands)

12.15 – 12.30

VIsualiZation of Asymtomatic atherosclerotic disease for optimum cardiovascular prevention – VIPVIZA – a RCT nested in routine care in Västerbotten Intervention Programme, Sweden
Ulf Näslund (Sweden)

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Session II. INFLAMMATION AND VASCULAR BIOLOGY
Organized and chaired by Katariina Öörni (Finland) and Tanja X. Pedersen (Denmark)

12.30 – 12.55

Modelling atherosclerosis in animals – possibilities and limitations
Jacob Bentzon (Denmark) 

12.55 – 13.00

Discussion

   

13.00 – 14.00

Lunch

14.00 – 15.00

General meeting of the Scandinnavian Society for Atherosclerosis Research
Open for all participants, decision on next year’s topics and chairpersons

Afternoon free for the Louisiana Museum of Modern Art (5 min walk), beach (5 min walk),
Kronborg, the castle of Hamlet (12 min by train) or downtown Copenhagen (50 min by train)

16.30 – 18.00

The traditional soccer match between countries
Remember to bring sports clothing and suitable footwear

18.00 – 19.00

Dinner


Session II. INFLAMMATION AND VASCULAR BIOLOGY - CONTINUED
Organized and chaired by Katariina Öörni (Finland) and Tanja X. Pedersen (Denmark)

19.00 – 19.25

Oxidation, ECM modification and atherosclerosis
Michael Davis (Denmark)

19.25 – 19.30

Discussion

19.30 – 19.45

Depletion of the Androgen Receptor in Osteoblasts Protects Against Abdominal Aortic Aneurysms in Male Mice
Marta Lantero Rodriguez (Sweden)

19.45 – 20.00

β – cyclodextrin reduces cholesterol crystal – induced inflammation through modulating complement activation
Siril Skaret Bakke (Norway)

20.00 – 20.15

Extracellular lipid particles accumulating in human carotid artery intima induce sterile inflammation in macrophages
Katariina Öörni (Finland)

20.15 – 20.45

Coffee, posters and exhibitions

20.45 – 21.00

Effect of the GLP – 1 analogue liraglutide on atherosclerosis and kidney fibrosis in moderate uremia
Line Stattau Bisgaard (Denmark)

21.00 – 21.15

Association between anti – citrullinated protein antibodies and long – term mortality in patients with ST – segment elevated myocardial infarction
Daniël van der Velden (The Netherlands)

21.15 – 21.30

Group IIA secretory phospholipase A2 (sPLA2 – IIA) predicts graft failure and mortality in renal transplant recipients by mediating decreased kidney function
Uwe Tietge (The Netherlands)

21.30 – 21.45

Comprehensive metabolic profiling of statin therapy: longitudinal evidence and mendelian randomization
Peter Würtz (Finland)

21.45 –

Pub will be open

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Friday, April 15, 2016

 

08.00 – 09.00

Breakfast.

 

Session III. LIPOPROTEINS AND LIPID TRANSPORT
Organized and chaired by Vesa Olkkonen (Finland) and Patrick Rensen (The Netherlands)

09.00 – 09.25

The role of TM6SF2 in VLDL TG secretion, NAFLD and CVD risk
Stefano Romeo (Sweden)

09.25 – 09.30

Discussion

09.30 – 09.45

Unstable LDL – Novel mechanism of atherogenesis and link to cardiovascular deaths
Maija Ruuth (Finland)

09.45 – 10.00

A loss – of – function variant in OSBPL1A predisposes to low plasma HDL cholesterol levels and impaired cholesterol efflux capacity
Vesa Olkkonen (Finland)

10.00 – 10.15

Increased lipoprotein binding to arterial proteoglycans and normal macrophage cholesterol efflux capacity characterize CKD dyslipidemia
Matteo Pedrelli (Sweden)

10.15 – 10.30

PCSK9 impacts obesity and metabolic syndrome development in animal models
Giuseppe Danilo Norata (Italy)

10.30 – 11.15

Coffee, posters and exhibitions

 

________________

 

11.15 – 11.40

Making and breaking ubiquitin chains in cholesterol metabolism
Noam Zelcer (The Netherlands)

11.40 – 11.45

Discussion

11.45 – 12.00

Ezetimibe in combination with simvastatin reduces remnant – cholesterol without affecting biliary lipid concentrations in gallstone patients
Paolo Parini (Sweden)

12.00 – 12.15

BCG lowers plasma cholesterol and delays atherosclerotic lesion progression
Andrea van Dam (The Netherlands)

12.15 – 12.30

FGF21 lowers plasma triglycerides by accelerating lipoprotein catabolism in white and brown adipose tissues
Christian Schlein (Germany)

12.30 – 12.45

Unravelling the mechanism and importance of brown adipose tissue whole lipoprotein uptake
Alexander Fischer (Germany)

12.45 – 14.00

Lunch

 

 

Session IV. OTHER TOPICS
Organized and chaired by Paolo Parini (Sweden) and Jeanine R. Lennep (The Netherlands)

14.00 – 14.25

Natural history of carriers of PCSK9 mutations
J.C.Defesche (The Netherlands)

14.25 – 14.30

Discussion

14.30 – 14.45

The body mass index value associated with the lowest mortality increased from 1976 – 78 through 2003 – 13: three cohort studies of the general population
Børge G Nordestgaard (Denmark)

14.45 – 15.00

Cold Regulated Bile Acid Synthesis Shapes the Gut Microbiome
Anna Worthmann (Germany)

15.00 – 15.15

Altered cerebral cholesterol homeostasis contributes to cognitive decline in an Alzheimer's disease mouse model with diabetes mellitus
Monique Mulder (The Netherlands)

   

15.15 – 15.30

LpPLA2 in Gestational Diabetes Mellitus – A protective system for placenta and fetus?
Christian Wadsack (Austria)

 

15.30 – 16.15

Coffee, posters and exhibitions

 

16.15 – 16.40

Diabetes in a dish: Human cellular models for the control of glucose homeostasis
Marine Kraus (Switzerland)

16.40 – 16.45

Discussion

16.45 – 17.00

Soat2 depletion improves liver steatosis and insulin sensitivity
Osman Ahmed (Sweden)

17.00 – 17.15

Non – alcoholic fatty liver disease as a cause of ischemic heart disease: a Mendelian randomization study and meta – analysis of 170,998 individuals
Bo Kobberø Lauridsen (Denmark)

17:15 – 17:30

Liver – humanized mice exhibit lipoprotein – specific phenotypes when grafted with human hepatocytes from different donors
Mirko Enea Minniti (Sweden)

17.30 – 19.00

Time free

 

19.00 – 19.30

Cocktail

19.30 –

Banquet and dancing

   

Saturday, April 16, 2016

08.30 – 10.00

Breakfast 

10.00

Departure

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Have a nice trip back home!!!